Transferring energy from big molecules into more useable forms
eg From sugar to ATP and NADPH
Anabolism
Building new molecules
Protein ,lipids and carbohydrates
complex molecules
Catabolism
Extracting energy out of Food
Vitamins Required
Thiamine [Vitamin B1 ] used as TPP
Riboflavin [Vitamin B2] used as FAD
Niacin ( nicotinic acid) [Vitamin B3 ] used as NAD and NADP
Pantothenic acid used as Coenzyme A
Pyridoxine [Vitamin B6 ] used as Pyidoxyl Phosphate
Deficiencies of "catabolic
enzymes"
Symptoms are mostly related to lack of available energy
Retarded growth
muscle weakness
brain damage
dermatitis
anaemia
Specific Deficiency diseases
Thiamine
Berri-berri
Riboflavin
Corneal ulceration Cataracts
angular stomatitis (dermatitis in mouth angle)
Niacin
Pellagra
4Ds = Diarrhoea, Dermatitis, Dementia and Death
Pantothenic Acid
low blood cholesterol
burning hands
Anabolic vitamins
Used in synthesising larger molecules
Pyridoxine
Interconversion of amino acids
Niacin
as NADPH need for most synthesis reactions
Niacin is also used in catabolic as well as anabolic pathways.
Folic acid
Vitamin B12
Ascorbic acid
Biotin [Vitamin H]
Deficiencies of "anabolic
vitamins"
May be similar to Catabolic inadequacy
energy needed for all anabolism
Symptoms are mostly related inability to synthetise material need for tissues
that are tuned over ( replaced) quickly.
Some parts of the body are slowly renewed
Adult brain
Other tissues are replaced very quickly
Tissue that are turned over
quickly
Red Blood Cells => Anaemia
Skin cells => Dermatitis
Lining of GIT => diarrhoea and malnutrition
hair =>
bone =>
Immune system => infections and cancer
Specific Deficiency diseases
Folic Acid
Hospital anaemia
Cooked food kept warm to long
Vitamin B12
pernicious anaemia
lack of ability to absorb vitamin in food
intrinsic factor made in stomach
loss of weight
Vitamin C
Scurvy
Causes of Deficiency Diseases
Dietary inadequacy
Inherited higher requirement
Ingestion of anti-nutritive substances
Dietary Sauces
NO single food has all the vitamins
But some food have NO vitamins
Referred to as "empty kilojoules" e.g.:
white sugar, processed vegetable oil
lollies, alcohol
Complimentary foods
The lack in some foods is made up in others
Hence "Eat a wide variety of Foods" and the "Five
Food Groups"
Five Food Groups
The lack in each group is made up in others
Group 1 Bread and Cereals Vitamins B1 B2 B3
Group 2 Milk and Cheese Vitamins B12, Ca
Group 3 Vegetables and Fruit Vitamin B3, Folate
Group 4 Meats , Fish & Poultry Vitamin B (Group),
Folate , Fe, Zn.
Group 5 Fats and Oil Fat soluble vitamins
The End
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